Benfotiamine
www.vitamindeal.com
Overstock Sale!Return FormOrder TrackingView CartCompany InfoHomeFree ShippingBest SellersNew ProductsShop By BrandShop By CategoryBeauty & JewelryBreast EnhancementDiet & Weight LossSexual PleasureJoint SupportWell BeingBody BuildingBrain & HeartVitaminDeal Home
VitaminDeal.com Logo
VitaminDeal Daily Deal VitaminDeal Spacer
VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer
VitaminDeal Daily Deal
Cockstar, Male Sexual Enhancement, 14 CapsulesCockstar, Male Sexual Enhancement, 14 Capsules
$17.97
VitaminDeal Daily Deal VitaminDeal Spacer
VitaminDeal Daily Deal VitaminDeal Spacer
VitaminDeal Tabs Diet & Weight Loss VitaminDeal Bar Intimacy Deals VitaminDeal Tabs Designer Fragrance VitaminDeal Tabs Body Building Deals VitaminDeal Tabs Beauty & Jewelry VitaminDeal Tabs Herbal Deals VitaminDeal Tabs Health Concern A-Z VitaminDeal Tabs Exotic Lingerie VitaminDeal Tabs
VitaminDeal Header
     
VitaminDeal Quick View
ALRI
SNAC
VPX
MRI
BNRG
MHP
HPF
ANSI
GU
pes
BSN
HDT
FRS

Best Sellers
Bookmark This Site
Free Newsletter
VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer
VitaminDeal Spacer VitaminDeal Spacer
Sign up for our free newsletter with monthly savings, coupons and great deals on hot items.
VitaminDeal Spacer VitaminDeal Spacer VitaminDeal Spacer
Free Newsletter
VitaminDeal Customer Quotes

VitaminDeal Visual Shop
VitaminDeal Spacer
Home > Herbal Deals > Benfotiamine
Home > Shop By Category > Herbal Deals > Benfotiamine

Benfotiamine


                         



Doctor's Best
Benfotiamine, 120 Veggie Caps, 150mg, From Doctor's Best
 
Benfotiamine, 120 Veggie Caps, 150mg, From Doctor's Best
Was: $29.99
Our Price: $13.50, 3/$39.75, 6/$78.00
Cost Per Serving: $0.11
 
Source Naturals
Benfotiamine, 60 Tablets, 150 mg, From Source Naturals
 
Benfotiamine, 60 Tablets, 150 mg, From Source Naturals
Was: $21.99
Our Price: $11.50, 3/$33.75, 6/$66.00
Cost Per Serving: $0.19
 


               
Benfotiamine

Benfotiamine is a form of Vitamin B-1 used in Germany for the treatment and prevention of diabetic health complications.

Advanced Glycation Endproducts, or “AGEs” as they’re appropriately called, are the end result of the complex chemical process through which the structure of proteins is warped by exposure to sugars or by other, much more reactive molecules. AGE chemistry is the cause of the “browning” you see when you roast a chicken or make toast, but the same “browning” chemistry is at work in your body every day of your life. In your arteries. In your kidneys. In your heart, your eyes, your skin, your nerves. In every cell, the sugar that your body uses for fuel is busily at work at this very moment, caramelizing your body through exactly the same chemical processes that caramelize onions or peanut brittle.

Glycation math is simple: more sugar equals more AGEd proteins. As a result, people with diabetes begin to feel the effects of glycation at much younger ages than do people with more normal blood sugar levels. Watching people with diabetes age is like watching “normal” aging played on fast-forward. Slowly, imperceptibly, AGE reactions create chemical handcuffs, which gum up your proteins, deactivate your enzymes, trigger unhealthy biochemical signaling in your cells, and damage your DNA. Aging you.

Two Ways to AGE

There are two major ways that AGEs can form inside the body. One way is through a simple series of chemical reactions known as the “Maillard Pathway,” known from food chemistry for a century.

But more recently, scientists have come to understand another pathway of AGE formation – a distinctly biological pathway, which only occurs within your cells because of the body’s metabolism of carbohydrates.

When blood sugar levels rise, some key kinds of cell – including- nerve cells (neurons) and the cells that make up the fine blood cells of the retina of the eye and the filtering units (glomeruli) of the kidney – are also flooded with glucose. The resulting high sugar levels within these cells cause a logjam in the normal cellular metabolism of glucose. This backlog results in a buildup within the cell of super-reactive glucose-metabolic intermediates known as triosephosphates. And once that happens, the excess triosephosphates attack the surrounding proteins, lipids, and DNA, causing AGE damage from within the heart of the cell. It’s these cells are thus the most vulnerable to the complications of diabetes.

Drugs do exist which can inhibit the formation of AGE, but none are available on the market as yet, and one of the most promising candidate (aminoguanidine) has shown signs of toxicity in human trials and appears to have been abandoned by its developers. On the other hand, some companies are selling supplements are marketed as “AGE-inhibitors.” But while many of the herbs and other nutrients may be valuable, and many even inhibit AGEing in a test tube, there’s no evidence that most of these “AGE-blocking” ingredients have any effect on AGEing in your body at the dosages used. Examples include thyme extract, inositol, acetyl-L-carnitine, taurine, and a whole host of antioxidants (including n-acetyl-cysteine (NAC) and flavonoids, such as quercetin and resveratrol).

TPP: Our Hero … in Chains!

There is a nutrient that could, in theory, pack a potent wallop against the AGE onslaught: Thiamin Pyrophosphate (TPP), the active coenzyme form of the B-complex vitamin thiamin. In 1996, researchers showed that TPP could step in to stop AGE formation at the most important point in the process: the late, irreversible conversion of Amadori products into full-blown AGEs. What’s more, TPP can exert a two-pronged AGE-inhibiting effect in the body, because boosting TPP in cells stressed by high glucose concentrations opens up an important biochemical “safety valve” in the normal metabolism of blood sugar through an enzyme known as transketolase. Activating transketolase allows the body to shunt excess triosephosphates into a safe alternative metabolic pathway, preventing the logjam that leads to the buildup of triosephosphates and the formation of AGE.

Unfortunately, this does not mean that loading up on regular thiamin (vitamin B1) will free you from glycation’s sticky shackles. The problem is that your body’s ability to absorb and metabolize conventional thiamin supplements is very limited. In fact, no matter how much thiamin you take, you don’t materially increase plasma levels beyond what you get from the first 12 milligrams of the dose. And then getting thiamin into the cells to do its job is just as tricky.

You might think that you can get around this problem by taking supplements containing TPP itself, instead of plain old thiamin. Unfortunately, as part of the normal cellular absorption process, specific enzymes actually strip TPP of its phosphate groups. As a result, you get no additional AGE-battling benefit from taking preformed thiamin pyrophosphate instead of standard thiamin. In fact, when you take supplements based on TPP itself, studies show that thiamin levels and biological activity are actually lower than if you take the same amount of regular thiamin!

Benfotiamine: the TPP Solution

Fortunately, an effective way to boost thiamin pyrophosphate in your cells does exist: Benfotiamine (S-benzoylthiamine-O-monophosphate). Benfotiamine is the most potent of the allithiamines, a unique class of thiamin-derived compounds present in trace quantities in roasted crushed garlic and other vegetables from the Allium genus (such as onions, shallots, and leeks). Benfotiamine’s unique open-ringed structure makes it able to pass directly through cell membranes, readily crossing the intestinal wall and being taken straight into the cell.

As a result, your body absorbs Benfotiamine better than thiamin itself, and levels of thiamin and TPP remain higher for longer. Thiamin absorption from Benfotiamine is about five times as great as from conventional thiamin supplements. And the effect is even more impressive at the tissue level: brain and muscle, for instance, take in five- to twentyfive-fold as much thiamin in the form of allithiamines as they do of an equal amount of regular thiamin. And Benfotiamine is even more bioavailable than the other allithiamines, including thiamin tetrahydrofurfuryl disulfide/TTFD. Yet Benfotiamine is actually less toxic than conventional thiamin supplements!

By effectively increasing levels of thiamin itself, Benfotiamine dramatically boosts AGE-fighting thiamin pyrophosphate and cell-shielding transketolase activity in your body.

Shielding Nerve Structure

While most “anti-AGE” supplements rely on test-tube “browning” experiments as the “evidence” of efficacy, Benfotiamine has been proven in multiple real-world human and animal studies to reduce AGE formation and support tissue structure and function in diabetics.

Most impressively, many randomized, double-blind, placebo-controlled human trials have proven that Benfotiamine powerfully supports nerve function in diabetic neuropathy. In one trial, 24 people suffering with diabetic neuropathy took either Benfotiamine (plus doses of common B6 and B12 similar to those used in mutivitamins) or a look-alike dummy pill, spread out into three pills over the course of the day, for twelve weeks. The participants started with 320 milligrams of Benfotiamine per day for the first two weeks, followed by 120 milligrams for the rest of the trial. Before and after the trial, the function of patients’s nerve cells were tested using nerve conduction velocity (NCV) and vibratory perception threshold (which tests the nerves’s sensitivity by determining the lowest level at which vibrations applied at key nerve sites are first felt).

At the end of the trial, the vibration perception threshold had “clearly” improved by 30% in those who had taken the Benfotiamine supplements, while it had worsened in the placebo group by 5% at one site and by 32% at another. At the same time, people taking Benfotiamine experienced statistically significant improvements in nerve conduction velocity from the feet, even as this aspect of nerve function deteriorated in those taking the look-alike pills!

The power of Benfotiamine to improve vibratory perception threshold and nerve conduction velocity have been confirmed in other trials. Clinical trials have also shown that Benfotiamine supports nerve function in diabetics as measured by many other methods. For instance, Benfotiamine users experience a 50% reduction in diabetic nerve pain, along with an increased ability of the nerves to detect an electrical current, respond to electrical stimulation, and regulate the heartbeat Similarly, Benfotiamine prevents this loss of control from happening in the first place in diabetic dogs. In another human clinical trial, a B-vitamin combination using Benfotiamine as its thiamin source was put head-to-head with a B-complex supplement that included a megadose of conventional thiamin. Benfotiamine proved its effectiveness on several of these key parameters, while the standard thiamin pill failed.

These benefits are not due to changes in blood sugar levels (either fasting, or after a meal, or averaged over several months (as measured by HbA1c), or improvements in metabolic benchmarks. They are the direct results of Benfotiamine’s AGE-fighting, metabolic-balancing powers.

Benfotiamine in Other Vulnerable Tissues

More recently, new studies have begun to document Benfotiamine’s ability to shield other tissues from AGE damage. One just-published study tested the ability of thiamin and Benfotiamine to protect diabetic rodents’ retinas from the ravages of AGE.

The researchers then gave one group of diabetic rodents Benfotiamine supplements, and left another group unsupplemented, keeping a third group of nondiabetic animals as a control group. Nine months later, they examined the animals’ eyes, testing the level of AGE in their retinas, examining metabolic abnormalities of the cells, and looking for acellular capillaries (the dead husks left behind when the cells of the tiny blood vessels of the eye die).

Benfotiamine supplements normalized AGE levels in the diabetics’ retina, as well as several key metabolic parameters within the diabetic animals’ cells – without influencing body weight or blood sugar (as measured by HbA1c). More importantly, Benfotiamine prevented the AGE-associated retinal damage. After nine months of diabetes, diabetic animals had suffered three times as many acellular capillaries as were found in healthy animals. But with the protection afforded by Benfotiamine, the number of acellular capillaries in the supplemented diabetics was indistinguishable from that of their normal, healthy cousins!

And there’s another AGE-related disease that researchers believe Benfotiamine may fight: the loss of kidney function which accompanies “normal” aging, and which is accelerated by diabetes. Dr. Paul Thornalley of the University of Essex has just completed a study designed to see if Benfotiamine will protect diabetic rodents against kidney damage. While the results have not yet been published, Dr. Thornalley has indicated that both megadose thiamin and Benfotiamine caused clear-cut reductions in the leakage of protein – with Benfotiamine showing itself to be the superior intervention. A second study is now underway to see if Benfotiamine will actually improve kidney function in diabetic animals with pre-existing kidney damage, as it has already been shown to do in the nerves of diabetic animals and humans.

The End of an AGE

These are not test-tube studies. The results experienced when taking Benfotiamine occur not merely in labs, but in lives: in the bodies – and in the health – of living things, from experimental animals to human beings. In Benfotiamine, we finally have a proven way to protect tissues from the AGE assault.


Copyright © VitaminDeal.com


Popular Product
General Info Heart Health Bone Support Joint Health Digestive Health Diabetes Health Personal Fitness Men's Health Women's Health Kids & Teens Overall Wellness


*These statements about Benfotiamine have not been evaluated by the Food and Drug Administration. Benfotiamine is not intended to diagnose, treat, cure, or prevent any disease.


Recently Viewed Items

VitaminDeal Spacer Customer Service
Track Your Order
Return Policy
Submit Return Request
Contact Us
View FAQ
Customer Service
Printable Order Form
Authorization Form
Top Reasons to Shop
VitaminDeal Spacer Shopping Helper
Shop at VitaminDeal.com
Shipping Info
Payment Info
Return Policy
Privacy Policy
Security Guarantee
Shoppers Review
Track My Order
VitaminDeal Spacer Company Information
About Us
Contact Us
Office Hours & Location
Testimonials
Site Map
Privacy Policy
Home
Terms and Conditions


VitaminDeal Quick View
Bodybuilding Deals
30 Day Vitamin Pack
Prohormones (Andro Free Formula)
Antioxidants
Anti Estrogen
Electrolyte Replenish Formula
> more
Diet and Weight Loss
Apple Cider Vinegar
Fat Loss Topical Cream
Fat Burners
Specialty Weight Loss
Diuretic Water Reduction
> more
Herbal Deals
5 - HTP
7 KETO
AAKG
Acai
Acetyl L Carnitine
> more
Herbal Deals
5 - HTP
7 KETO
Acai
Alfalfa
Aloe Vera
> more
Designer Fragrance
Pheromone Fragrance
Alfred Dunhill
Aramis
Bijan
Britney Spears
> more
Beauty & Jewelry
Crystal Jewelry
Jewelry
Anti Aging Support
Adrenal Support
Allergy Relief
> more
Deals For Him
Sex Drive Booster
Soft Erection
Premature Ejaculation
Penis Enlargement
Orgasm Intensifier
> more
Deals For Her
Sex Drive Booster for Her
Breast Enlargement
Menopausal Support
Orgasm Enhancer
PMS Support
> more
Intimacy Deals
Deals For Him
Deals For Her
Personal Lubricant
Libido Booster
Condoms
> more
Exotic Lingerie
Shoes, Heels and Platform
Baby Dolls
Body Jewelry and Sensual Wear
Bras
Bustiers
> more
Health Concern A to Z
Acne Formula
Acid Neutralizing Formulas
Alkalyzing Formulas
Allergy Relief
Alzheimer's Disease
> more
Shop By Brand
2:1 Protein Bars
4 Sport Life
4Ever Fit
4ever Pets (4everPets)
8 in 1 Pet Products
> more
Shop By Brand
2:1 Protein Bars
4 Sport Life
4Ever Fit
4ever Pets (4everPets)
8 in 1 Pet Products
> more
Shop By Category
New Product
Diet and Weight Loss
Intimacy Deals
Protein Powder
Bodybuilding Deals
> more
New Product
As Seen on TV
> more
Organic Formula
Organic Baby Formula
Organic Body Cleanse
Organic Deodorant
Organic Eye care
Organic Facial Formula
> more
Electronic and Gift Idea
Melissa & Doug
Water Filter System
Beads Handcraft Art
Aluminum Decor
Baby & Kids Lamp
> more
Best Sellers
A Best Sellers
B Best Sellers
C Best Sellers
D Best Sellers
E Best Sellers
> more
Customer Service
Shop at VitaminDeal.com
Customer Service

Shipping Info on Domestic & International
Track Your Order
> more
Health From The Sun


Health from the Sun Organic Flax $10.95


> more
SDC Nutrition





> more
Adept Nutrition





> more
Glennys





> more
Twinlab





> more
Champion Nutrition





> more
Genisoy





> more
QuickTrim





> more
Svelte


> more
Universal Nutrition
Universal Nox3 Blowout Sale
Universal Animal Stak 2 Instant Savings $24.97 Each.
Universal Animal Cuts Sale $30.25


> more
American Body Building





> more
Nutrakey





> more
Futurebiotics





> more
Pro Tan




> more
Nestle-Water


> more
Progryp





> more
Jelly Belly





> more
Honey Stinger





> more
Vitol





> more
iForce Nutrition





> more
Fitness Enterprise




> more
natures-best





> more
Mega-Pro





> more
Genomyx





> more
Vitalabs





> more
ALRI





> more
CTD Labs





> more
Athletic Edge Nutrition





> more
USP Labs





> more
RockTape





> more
StarChem Labs





> more
Bonk-Breaker





> more
SNAC





> more
PowerBar





> more
Genesis Nutrition





> more
Ronnie-Coleman





> more
CytoSport





> more
PrimaForce




Primaforce ZMA mineral Formula for Hormone Production $15.97 each.
> more
SciVation



Scivation Sesamin Formula, Reduce Bodyfat Naturally $22.97 each.

> more
Inner Armour





> more
NVE Pharmaceuticals





> more
Nutraceutics





> more
Peaceworks





> more
Himalaya





> more
Fahrenheit Nutrition





> more
Sex Drive Enhancer





> more
MRM Nutrition





> more
Top Secret Nutrition





> more
ANS-Performance





> more
live-long-nutrition





> more
Professional Supplements





> more
VPX





> more
Ostrim





> more
SpiderTech




> more
Beast-Sport-Nutrition




> more
Muscletech




> more
Cellucor





> more
MRI





> more
EAS Experimental and Applied Sciences

EAS Bars
> more
supreme-protein-bar



> more
german-american-tech





> more
giant-sports


> more
BNRG





> more
gaspari-nutrition





> more
Biotest
Biotest Hot Rox Extreme $32.97

Fahrenheit Fat Burner For Women $16.97


> more
muscle-marketing-usa


> more
Better Body Sports





> more
MHP



Increase Natural Testostone Now $43.97

> more
san-nutrition





> more
HPF





> more
ids-sports


> more
Chef Jay





> more
Myogenix





> more
Covaxil Laboratories


> more
Intramedic Research Group


> more
ProMera Health





> more
CNP Professional





> more
Axis Labs





> more
Redfine-Nutrition





> more
ANSI





> more
Dymatize Nutrition





> more
ast-sport-science

> more
X-Pain



> more
Muscle Pharm





> more
Absolute Nutrition





> more
Irwin Naturals





> more
labrada-nutrition





> more
Gamma O




> more
Living Essentials





> more
Baddas-Nutrition





> more
Clif Bar





> more
Right-Way-Nutrition




> more
Detoxify





> more
E Pharm


> more
Next Nutrition
Designer Protein Chocolate Only $14.95




> more
valeo-fitness-accessories





> more
MD-Research

> more
All American Pharmaceutical





> more
Promax
Promax best Tasting Protein Bar $12.97




> more
Optimum Nutrition

Optimum whey Gold Standar Chocolate Sale $15.97



> more
Prolab





> more
Infinite Labs





> more
Think Products





> more
Nutri-Force





> more
Brazilian-Diet


> more
Good Health Natural Foods





> more
Pinnacle




> more
molecular-nutrition





> more
GU





> more
MET-Rx




> more
Lenny & Larry's





> more
ISS Research





> more
Driven Sports



> more
4Ever Fit





> more
Hit Supplements





> more
pes





> more
LeCheek Nutrition





> more
Quest




> more
Bio-science Institute


> more
Evogen





> more
Weider Nutrition





> more
AmiLean


> more
Applied Nutriceuticals





> more
Anabolic Innovations





> more
TurboShaker





> more
Nutrition 53





> more
nx-labs

> more
PureFit





> more
Qnt International




> more
growing-naturals



> more
SportLegs


> more
F3-Nutrition





> more
Natures Research Nutritionals




> more
Muscleology





> more
BSN

BSN Epozine NT Sale $39.97
BSN No Xplode Muscle Volumizer $34.97


> more
Fusion Bodybuilding





> more
Genetic Solutions




> more
Paramount Products Group


> more
Come-Ready-Nutrition



> more
To Go Brands





> more
Thats It Nutrition




> more
dynamic-balance-nutrition

> more
Xtreme Formulations





> more
BPI Sports





> more
ext-sports

> more
KingFisher-Media





> more
RSP Nutrition





> more
vitazen



> more
nutrex-research

> more
VirMax





> more
Hi-Tech Pharmaceuticals





> more
C2O-Pure

> more
Applied Nutrition





> more
Devine-Health

> more
Muscle Warfare





> more
Purus Labs





> more
HDT





> more
NoGii





> more
no-opportunity-wasted





> more
Rickland-Orchards





> more
Runnin Wild Foods





> more
Betancourt Nutrition





> more
Animal Naturals





> more
Beauty-Fit





> more
Barndad Nutrition

> more
Convenient Nutrition




> more
NutriWorks




> more
FRS





> more
Integrated Supplements





> more
Fizogen





> more
isatori-global




> more
biogenetic-laboratories


> more
Celsius





> more
Forerunner Labs




> more
Advanced Muscle Science





> more
Controlled Labs





> more
EST Nutrition





> more
Genceutic Naturals
> more
Titan Support Systems





> more
MAN Sports





> more
ErgoGenix





> more
sexvoltz

> more
women-sex-drive-enhancer

> more
Lexxus
Viacreme Alura Stimulant $54.95




> more

Subscribe to VitaminDeal Weekly Promotions
VitaminDeal Promotion Add to Google Yahoo My MSN Add to My AOL Subscribe with Bloglines Subscribe in NewsGator Online add to del.icio.us
Bookmark VitaminDeal.com and Share with Friends

HACKER SAFE certified sites prevent over 99.9% of hacker crime. ecommerce provided by Yahoo! Small Business

The information provided on this site is for informational purposes only and is not meant to substitute for advice provided by a healthcare professional. The information provided should not be used for diagnosing, treating or prescribing medication for treatment of a disease or health-related condition. You should carefully read all information provided in product packaging and follow the appropriate directions for use. If you have or suspect that you have a medical problem, promptly contact your healthcare professional.



All models 18 years of age or older at the time of depiction. Custodian of Records (18 U.S.C. 2257)

Copyright © 2002-2014 VitaminDeal.com. Designated trademarks and brands are the property of their respective owners.

Questions? Comments? Please contact us.
VitaminDeal.com Privacy Policy
Tel: 1-626-363-9830       Toll Free: 1-877-332-5798


VitaminDeal Spacer
VitaminDeal Spacer
Benfotiamine
Irwin Naturals

Jarrow Formulas

Libigrow Product Sale

Vigor Labs Product Sale

Ultimate Nutrition Product
Save on Popular Ultimate Nutrition Products, Bulgarian Tribulus, Carb Block & more.
Instant Savings Price Starts at
$13.97 each

VyoTech 17 HD Sale
Save on this Popular Testosterone Amplifier Formula.
Price Below Wholesale at
$39.97 each

Biotest Hot Rox 72 Count
Extreme Fat Loss from Biotest Labs, Instant Savings Buy Now!
Why Pay More than Wholesale
Now at only $19.97 Each

Hyalogic Synthovial 7 Serum
Stretch Mark Repair Gel Compare made from Hyaluronic Acid
Popular Hyaluronic Acid Product
Unbeatable Price of $32.50

Elongate Enlargement for Men
All Natural supplement for Size Increase, Yes Size Does Matter!
Penis Enlargement that Works
Buy it Now at $25

Coral Calcium Supreme Sale
Instant Savings on Robert Barefoot Signature Coral Calcium Product
Original Formula not Imitation
Price as Low as $14.50

Smoke Away 3 Phase Kit
Want to Quit Smoking? Here is your Answer, As Seen on TV Product!
Stop the Craving NOW!
Buy it Now at $38.98

Barley Green Premium
Organic Green Grass Powder, Rich in Vitamin, Mineral and Antioxidant
Dr. Lorraine Day Endorsed
Price as Low as $36.95

VitaminDeal Spacer
VitaminDeal Spacer
Benfotiamine