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Cascara Sagrada is a medicinal plant whose bark is used primarily for relief from constipation. Traditionally it has been used as a folk remedy for chronic constipation, dyspepsia, as a tonic for the bowels, and a treatment for liver and gallbladder problems.
Cascara sagrada contains compounds called anthroquinones, which are responsible for cascara's powerful laxative effects. People use cascara sagrada for constipation.
A typical dosage of cascara is a 300 mg capsule taken in the early evening to stimulate a bowel movement in the morning. The laxative effect usually occurs 6 to 12 hours after cascara is taken.
Cascara sagrada should not be used for longer than 7 days in a row.
Pregnant or nursing women should not use cascara sagrada. Children should not use cascara sagrada.
Side effects of cascara may include strong cramping in the abdomen (due to muscle contractions, electrolyte imbalance (loss of potassium) and loss of body fluids, and dark pigmentation in the colon, called melanosis coli with longer-term use. Call your doctor if you experience bloody diarrhea, discolored urine, vomiting, or prolonged abdominal pain after using cascara.
There has been one report of the development of cholestatic hepatitis, complicated by portal hypertension, after use of cascara. Long-term use of anthraquinones has been linked to the development of colorectal growths (adenomas) and cancer.
Large doses of anthraquinones may cause bloody diarrhea or vomiting.
Long-term use can cause dependence.
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*These statements about Cascara Sagrada have not been evaluated by the Food and Drug Administration. Cascara Sagrada is not intended to diagnose, treat, cure, or prevent any disease.
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Cascara Sagrada
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