L-Carnitine
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Home > Shop By Category > Diet and Weight Loss > L-Carnitine
Home > Diet and Weight Loss > L-Carnitine

L-Carnitine


                         



Jarrow Formulas
L Carnitine 500, Turn Fat Into Energy, 100 Capsules, 500mg, Pharmaceutical Grade, From Jarrow
 
L Carnitine 500, Turn Fat Into Energy, 100 Capsules, 500mg, Pharmaceutical Grade, From Jarrow
Was: $42.99
Our Price: $22.11, 3/$66.24, 6/$132.36
Cost Per Serving: $0.22
 
NOW Foods
L-Carnitine, High Potency, Stable Tartrate Form, 180 Capsules, 500mg, From NOW
 
L-Carnitine, High Potency, Stable Tartrate Form, 180 Capsules, 500mg, From NOW
Was: $60.99
Our Price: $30.45, 6/$182.52
Cost Per Serving: $0.17
 
Twinlab
Mega L-Carnitine, Metabolizes Fat into Energy, 90 Tablets, 500mg, From Twinlab
 
Mega L-Carnitine, Metabolizes Fat into Energy, 90 Tablets, 500mg, From Twinlab
Was: $54.99
Our Price: $25.75
Cost Per Serving: $0.29
 
Ultimate Nutrition
L-Carnitine, 30 Tablets, 1000mg, L Carnitine, From Ultimate
 
L-Carnitine, 30 Tablets, 1000mg, L Carnitine, From Ultimate
Was: $26.99
Our Price: $12.97, 3/$38.25, 6/$75.00
Cost Per Serving: $0.43
 
Doctor's Best
L-Carnitine Fumarate, 60 Capsules, 500mg, L Carnitine Fumarate, From Doctor's Be
 
L-Carnitine Fumarate, 60 Capsules, 500mg, L Carnitine Fumarate, From Doctor's Be
Was: $29.99
Our Price: $13.97, 3/$41.25, 6/$81.00
Cost Per Serving: $0.23
 
Nature's Way
L-Carnitine, 60 Vcaps, 500 mg, L Carnitine, From Nature's Way
 
L-Carnitine, 60 Vcaps, 500 mg, L Carnitine, From Nature's Way
Was: $24.99
Our Price: $13.00
Cost Per Serving: $0.22
 
Source Naturals
L-Carnitine, Metabolic Energy, 120 Capsules, 250 mg, L Carnitine, From Source Natural
 
L-Carnitine, Metabolic Energy, 120 Capsules, 250 mg, L Carnitine, From Source Natural
Was: $14.99
Our Price: $8.25, 6/$48.00, 12/$93.00
Cost Per Serving: $0.07
 
Solaray
L Carnitine, 60 Capsules, From Solaray
 
L Carnitine, 60 Capsules, From Solaray
Was: $40.99
Our Price: $22.97, 3/$68.25
Cost Per Serving: $0.38
 
Twinlab
L Carnitine, 250 mg, 60 Capsules, From Twinlab
 
L Carnitine, 250 mg, 60 Capsules, From Twinlab
Was: $29.99
Our Price: $13.97
Cost Per Serving: $0.23
 
Twinlab
L Carnitine, 90 Capsules, From Twinlab
 
L Carnitine, 90 Capsules, From Twinlab
Was: $41.99
Our Price: $19.75
Cost Per Serving: $0.22
 
Country Life
L-Carnitine Caps 500 Mg W/B,6, 60 Capsules, From Country Life
 
L-Carnitine Caps 500 Mg W/B,6, 60 Capsules, From Country Life
Was: $39.99
Our Price: $19.97
Cost Per Serving: $0.33
 
Natrol
L-Carnitine Cellular Energy, 30 Capsules, 500mg, From Natrol
 
L-Carnitine Cellular Energy, 30 Capsules, 500mg, From Natrol
Was: $14.99
Our Price: $8.97
Cost Per Serving: $0.30
 
NOW Foods
L-Carnitine Pure Powder, 3 oz, From NOW
 
L-Carnitine Pure Powder, 3 oz, From NOW
Was: $39.99
Our Price: $19.96, 6/$119.58
 
NOW Foods
Acetyl-L-Carnitine, 90 Tablets, 750 mg, From NOW
 
Acetyl-L-Carnitine, 90 Tablets, 750 mg, From NOW
Was: $39.99
Our Price: $19.99, 6/$119.76
Cost Per Serving: $0.22
 
NOW Foods
Acetyl-L Carnitine, Brain Health, 100 Capsules, 500mg, Acetyl L-Carnitine, NOW
 
Acetyl-L Carnitine, Brain Health, 100 Capsules, 500mg, Acetyl L-Carnitine, NOW
Was: $27.99
Our Price: $17.50, 6/$104.82
Cost Per Serving: $0.17
 
IDS Sports
Acetyl L-Carnitine, 120 Capsules, From IDS
 
Acetyl L-Carnitine, 120 Capsules, From IDS
Was: $29.99
Our Price: $16.50, 2/$32.50, 4/$64.00
Cost Per Serving: $0.14
 
Jarrow Formulas
Acetyl L-Carnitine 500, Antioxidant Protection for Brain, 60 Capsules, 500mg, From Jarrow  Acetyl l Carnitine
 
Acetyl L-Carnitine 500, Antioxidant Protection for Brain, 60 Capsules, 500mg, From Jarrow Acetyl l Carnitine
Was: $29.99
Our Price: $10.50, 6/$61.50, 12/$120.00
Cost Per Serving: $0.17
 
Doctor's Best
Acetyl L-Carnitine (ALC), 60 Capsules, 500mg, Acetyl L Carnitine, From Doctor's
 
Acetyl L-Carnitine (ALC), 60 Capsules, 500mg, Acetyl L Carnitine, From Doctor's
Was: $21.99
Our Price: $9.97, 6/$58.50, 12/$114.00
Cost Per Serving: $0.17
 
Dymatize Nutrition
Acetyl L-Carnitine, 90 Capsules, Acetyl L Carnitine, From Dymatize
 
Acetyl L-Carnitine, 90 Capsules, Acetyl L Carnitine, From Dymatize
Was: $39.99
Our Price: $9.95, 6/$58.50
Cost Per Serving: $0.11
 
Jarrow Formulas
ALCA 500, Acetyl L, Carnitine Arginate, 100 Capsules, 500 mg, From Jarrow
 
ALCA 500, Acetyl L, Carnitine Arginate, 100 Capsules, 500 mg, From Jarrow
Was: $39.99
Our Price: $22.77, 3/$68.22, 6/$136.32
Cost Per Serving: $0.23
 
Kal
AcetylL Carnitine & Alpha Lipoic Acid, 60 Tablets, From Kal
 
AcetylL Carnitine & Alpha Lipoic Acid, 60 Tablets, From Kal
Was: $43.99
Our Price: $24.50, 3/$72.75
Cost Per Serving: $0.41
 
Solaray
Acetyl L Carnitine 500 Mg, 30 Vegetable Capsules, From Solaray
 
Acetyl L Carnitine 500 Mg, 30 Vegetable Capsules, From Solaray
Was: $13.99
Our Price: $7.75, 6/$45.90, 12/$90.00
Cost Per Serving: $0.26
 
Twinlab
Acetyl-L-Carnitine, Free Form Amino Acid, 30 Capsules, From Twinlab
 
Acetyl-L-Carnitine, Free Form Amino Acid, 30 Capsules, From Twinlab
Was: $31.99
Our Price: $17.97
Cost Per Serving: $0.60
 
Country Life
Acetyl L-Carnitine 500 mg, 120 VegiCaps, From Country Life
 
Acetyl L-Carnitine 500 mg, 120 VegiCaps, From Country Life
Was: $49.99
Our Price: $19.97, 3/$59.25, 6/$117.00
Cost Per Serving: $0.17
 
NOW Foods
Acetyl L-Carnitine Pure Powder, 3 oz, From NOW
 
Acetyl L-Carnitine Pure Powder, 3 oz, From NOW
Was: $39.99
Our Price: $20.00, 6/$119.82
 
Nature's Way
Acetyl L-Carnitine, 500 mg, 60 Vegetarian Capsules, From Nature∆s Way
 
Acetyl L-Carnitine, 500 mg, 60 Vegetarian Capsules, From Nature∆s Way
Was: $24.99
Our Price: $13.00
Cost Per Serving: $0.22
 
Olympian Labs
Acetyl L-Carnitine, 60 Vegetarian Capsules, 500 mg, From Olympian Labs
 
Acetyl L-Carnitine, 60 Vegetarian Capsules, 500 mg, From Olympian Labs
Was: $29.99
Our Price: $17.75, 4/$70.60
Cost Per Serving: $0.30
 
PrimaForce
Alcalean, 100% Acetyl L-Carnitine, 100 Capsules, From PrimaForce
 
Alcalean, 100% Acetyl L-Carnitine, 100 Capsules, From PrimaForce
Was: $29.99
Our Price: $14.50, 4/$57.00
Cost Per Serving: $0.14
 
Source Naturals
Acetyl L-Carnitine & Alpha-Lipoic Acid 650Mg, 60 Tablets, From Source Naturals
 
Acetyl L-Carnitine & Alpha-Lipoic Acid 650Mg, 60 Tablets, From Source Naturals
Was: $31.99
Our Price: $16.25, 3/$48.00, 6/$96.00
Cost Per Serving: $0.27
 
Source Naturals
Acetyl L-Carnitine, 60 Tablets, 500mg, From Source Naturals
 
Acetyl L-Carnitine, 60 Tablets, 500mg, From Source Naturals
Was: $29.99
Our Price: $14.50, 3/$42.75, 6/$84.00
Cost Per Serving: $0.24
 
Iron Tek
Essential Liquid Carnitine 1000, Natural Vanilla Flavor, 16 oz. From Iron-Tek
 
Essential Liquid Carnitine 1000, Natural Vanilla Flavor, 16 oz. From Iron-Tek
Was: $19.99
Our Price: $10.97, 3/$38.25, 6/$63.00
Cost Per Serving: $0.34
 
Twinlab
Mega L Carnitine Liquid, 12 oz, From Twinlab
 
Mega L Carnitine Liquid, 12 oz, From Twinlab
Was: $22.99
Our Price: $10.97
Cost Per Serving: $0.91
 
Ultimate Nutrition
L Carnitine, Carnitine Liquid, 12 oz, From Ultimate
 
L Carnitine, Carnitine Liquid, 12 oz, From Ultimate
Was: $19.99
Our Price: $10.98, 3/$32.25, 6/$63.00
Cost Per Serving: $0.46
 
NOW Foods
L-Carnitine Liquid, Double Strength Potency Pharmaceutical Grade, 16 oz. 1000 mg, From NOW
 
L-Carnitine Liquid, Double Strength Potency Pharmaceutical Grade, 16 oz. 1000 mg, From NOW
Was: $24.99
Our Price: $11.50, 6/$68.82
Cost Per Serving: $11.50
 
Dymatize Nutrition
Liquid L-Carnitine, BLUE RASPBERRY, L Carnitine, From Dymatize
 
Liquid L-Carnitine, BLUE RASPBERRY, L Carnitine, From Dymatize
Was: $29.99
Our Price: $10.25, 3/$30.00, 6/$58.50
Cost Per Serving: $0.33
 
Dymatize Nutrition
Liquid L-Carnitine, BERRY, L Carnitine, From Dymatize
 
Liquid L-Carnitine, BERRY, L Carnitine, From Dymatize
Was: $29.99
Our Price: $10.25, 3/$30.00, 6/$58.50
Cost Per Serving: $0.64
 
Dymatize Nutrition
Liquid L-Carnitine, ORANGE, L Carnitine, From Dymatize
 
Liquid L-Carnitine, ORANGE, L Carnitine, From Dymatize
Was: $29.99
Our Price: $10.25, 3/$30.00, 6/$58.50
Cost Per Serving: $0.64
 
Dynamic Health Laboratories
L-Carnitine Liquid, 1200 mg, Lemon Lime Flavor, 16 oz. L Carnitine, From Dynamic Health
 
L-Carnitine Liquid, 1200 mg, Lemon Lime Flavor, 16 oz. L Carnitine, From Dynamic Health
Was: $19.99
Our Price: $11.97
 
Prolab
L-Carnitine Liquid, Burn Fat For Energy, 12 oz. L Carnitine, From Prolab
 
L-Carnitine Liquid, Burn Fat For Energy, 12 oz. L Carnitine, From Prolab
Was: $23.99
Our Price: $11.97, 2/$22.99
 
Nature's Answer
Liquid L-Carnitine, Natural Raspberry Flavor, 16 oz, From Nature's Answer
 
Liquid L-Carnitine, Natural Raspberry Flavor, 16 oz, From Nature's Answer
Was: $22.99
Our Price: $11.48
 


               
L-Carnitine

L Carnitine is an important co-factor for energy production from fats

L-Carnitine is an amino acid found in high concentrations in human heart and liver tissue, where it participates in metabolizing fatty acids into energy by the mitochondria. L-Carnitine also facilitates the metabolism of carbohydrates and enhances the rate of oxidative phosphorylation L-Carnitine works synergistically with CO-Q10, an antioxidant and energy co-factor that is found in the inner membrane of the mitochondria.

What is L-Carnitine?
L-carnitine is a trimethylated amino acid that plays essential roles in many areas of the body, including fatty acid translocation and muscle function. Carnitine is also acetylated into the ester Acetyl-L-carnitine (ALCAR) in the brain, liver, and kidney. ALCAR also plays a variety of roles in the body, including increasing acetylcholine production and stimulation of protein and membrane phospholipid synthesis. Orally administered L-carnitine and ALCAR have profound anti-aging and nutrient repartitioning properties, and the effects of supplementing with them have been extensively researched in many areas, including exercise performance, weight loss, treatment of Alzheimer's, Parkinson's, diabetic neuropathy, depression and many other neurological disorders, treatment of alcoholism, treatment of cardiovascular diseases, insulin resistance, and many others.

What benefits does L-Carnitine have?

  • Cardiovascular benefits - The carnitines have considerable potential in the treatment of cardiovascular disease. Rodent studies with L-carnitine have shown decreased triglyceride and cholesterol levels and protection against arrhythmia and ischemia, and a study with ALCAR found a reversal of the age-related decline in mitochondrial function in the heart. A study on the three-year survival rate of patients with dilated cardiomyopathy supplemented with L-carnitine (n=37) or placebo (n=33) found one death in the L-carnitine group and six in the placebo group, and concluded that L-carnitine had a considerable effect. Another study found over a 10% reduction in cardiac events following suspected myocardial infarction, and other human studies have found reduced arrhytmia, significant improvement in patients with congestive heart failure, and reduced cholesterol and triglycerides.

  • Improved cognitive function - ALCAR plays a strong role in the brain in many ways, and has beneficial effects in many conditions including Alzheimer's and Parkinson's. Studies in aged rodents show markedly improved memory and learning capacities, while studies in younger rodents show a variety of promising effects as well. Other rodent studies have shown that ALCAR significantly protects the brain against a variety of stresses, such as ischemia and repurfusion and mitochondrial uncoupling. It also protects against peripheral nerve trauma, "almost eliminating neuron loss", and in vitro neuronal apoptosis. ALCAR also increases levels of dopamine, amino acids, and acetylcholine in the brain, as well as facilitating cholinergic activity.

    One of the primary mechanisms for the improved cognitive function and anti-aging properties seen with ALCAR is its ability to prevent oxidation and inflammation. Administering ALCAR reduces lipid peroxidation, prevents or reverses many age-related increases in markers of oxidative and inflammatory events in the cortex, reduces damage to nucleic acids (DNA/RNA) and proteins, and also increases the levels of other antioxidants in the brain. Administering ALCAR also prevents mitochondrial decay, restores depleted ATP levels, and restores the activity of many key enzymes that decline with age such as carnitine acetyltranferase, mitochondrial complexes III and IV, sodium potassium adenosine triphosphatase, and glutathione-S-transferase.

    ALCAR supplementation is also accompanied by many positive structural changes in the brain in both the young and the old. It stimulates nerve growth factor (NGF) binding, and rodent studies indicate significantly more regenerative elements and reduced degenerative elements. A study that measured the regenerative capacity of myelinated fibers in young and old rats found that ALCAR significantly increased the density of regenerating myelinated fibers (RMF) and increased the density of axon diameters in both, as well as reducing degenerative elements, and another rat study with ALCAR found increased synaptic numeric densities and improvements in energy provision at nerve terminals in both young and old rats, as well as 10-20% increases in synapses smaller than .08 microns.

  • Improved hearing and visual function - Two animal studies indicate a significant reduction in noise-induced and age-induced hearing loss with ALCAR. One measured outer hair cell (OHC) density after three weeks of noise exposure, and found less than a 10% reduction with ALCAR as opposed to 60% with placebo, and noise induced threshold shifts were less than 10 dB in the ALCAR group as opposed to 30-35 dB with placebo. A six-week study with aged rats found ALCAR to improve auditory thresholds by upregulating mitochondrial function and reducing oxidative stress.

    Improvements in visual function have been noted as well. A preliminary study on guinea pigs found an improvement in alignment to ocular responses and enhancement of optical nerve growth, and hypothesized that ALCAR can increase visual function. In vitro, ALCAR also prevents the buildup of advanced glycation end products (AGEs) in the eye, which are a known cause of macular degeneration.

  • Reduced stress and depression - In rats, ALCAR protects against the decreases in dopamine and testosterone that normally occur after exposure to both acute and chronic stress and decreases other markers of stress, and no tolerance develops to this effect. Preliminary human studies in the elderly and those undergoing treatment for certain conditions indicate a reduction in depression and fatigue and an improvement in quality of life.


  • L-Carnitine is primarily involved with transporting long-chain fatty acids from the cell cytosol into the mitochondria. Since long chain fatty acids are oxidized (burned) in the mitochondria, L- Carnitine facilitates production of energy from fat. Oxidation (combining with oxygen) of the BCAAs is facilitated by L- Carnitine, providing a link between protein catabolism and cellular energy. Skeletal muscle contains 90% of total body carnitine in humans.

    What application does L-Carnitine have?
    The carnitines are excellent supplements for athletes, as well as anyone who wants to look and feel thier best. Studies with both ALCAR and L-carnitine have shown that they have potent nutrient repartitioning effects, and there are some studies indicating that L-carnitine can increase exercise performance.

    In one study, both young and old rats were supplemented with ALCAR and compared with age-matched controls. Nutrient partitioning and muscle mass and function were among the factors measured. Body weight did not differ significantly between the two groups, but there were strong differences in the fat to protein ratios. The young rats fed ALCAR had slightly higher body protein levels (not statistically significant) and significantly less body fat, while the old rats fed ALCAR had much high body protein levels and the same amount of body fat. ALCAR may be especially useful for older people, as one rat study found that long-term administration prevents the progressive increase in the size of fat cells that normally occurs with age.

    Another study looked at the effects of carnitine (.68 g) and choline (.94 g) supplementation on fat metabolism in healthy women. In the treatment groups, body fat decreased .7-1.3% over 35 days (as opposed to no difference in the placebo group). They also found that when the supplemented groups exercised, the ability to utilize fat as energy substrate increased (5). Animal studies have also shown L-carnitine to reduce obesity and improve nitrogen utilization. However, there has been one human study in moderately obese premenopausal women in which no weight loss or repartitioning effect was found with L-carnitine.

    When looking at the effects of the carnitines on exercise performance, we no longer have to rely so much on animal studies. Various studies have shown that L-carnitine improves exercise performance in people with heart problems or impaired exercise tolerance, as well as people recovering from hemodialysis. However, the influence on exercise performance on healthy individuals is less clear. L-carnitine definitely changes the response and effects of exercise, as evidenced by decreased muscle soreness and decreased pyruvate and lactate concentrations and higher ALCAR concentrations post-exercise, as well as studies showing it to increase utilization of fat as a fuel source during exercise. A study with L-carnitine L-tartrate also showed it to favorably effect many markers of recovery from squat exercises. The real world effect of this is not conclusively known, and two recent reviews stated that further studies are needed before the effect can be determined on healthy individuals. Regardless of the present lack of human studies showing a definite ergogenic effect, the nutrient partitioning properties and improved recovery alone make carnitine a worthwhile supplement, and there are also many added benefits.

    How does Carnitine work?
    Carnitine's primary job is in the regulation of cellular metabolism, and it closely interacts with coenzyme A in a variety of reactions. It is required for fatty acid oxidation, and this is the primary theoretical reason for improved exercise performance, as improved fatty acid oxidation will preserve muscle glycogen and improve ATP production. It was recently confirmed that supplemental carnitine increases long-chain fatty acid oxidation in healthy individuals without carnitine deficiency, providing more evidence for an ergogenic benefit. Enhanced fatty acid oxidation and cellular metabolism is also the proposed mechanism of action for the nutrient partitioning benefits.

    Additionally, carnitine is a potent antioxidant (especially in combination with ALA) and there is evidence that it increases exercise performance for this reason. A Russian study found that both L-carnitine and ALCAR increased running speed and endurance in trained animals, and that the increase was proportional to their antioxidative activity. Another strong antioxidant is melatonin, and ALCAR has also been shown to increase melatonin levels.

    Are there any side effects?
    Carnitine has no toxicity, teratogenicity, contraindications, or drug interagions. There are very few side effects associated with carnitine use, and no serious side effects have been reported. Some users report nausea or stimulation, but these tend to be transient and disappear with time. There are also many anecdotal reports of more vivid dreams.

    L-Carnitine's Function during Aerobic Exercise:
  • L Carnitine Helps Increase Fat Metabolism
  • L Carnitine Increases Endurance
  • L Carnitine Improves Definition
  • L Carnitine Increases Utilization of Fatty Acids as Energy
  • L Carnitine Decreases Lactate Build Up
  • L Carnitine May Help in the Reduction of Ketones in the Blood. (important for diabetics)



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